BDBM541815 US11267824, Example 34a

SMILES CC1(C)CCC(C[C@@H](O)c2c(sc3cncn23)C2CC2)C1

InChI Key InChIKey=PVGOVXMNFSLUNP-GLGOKHISSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541815   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541815(US11267824, Example 34a)
Affinity DataIC50:  262nMAssay Description:TDO2: Recombinant human TDO comprising amino acids 19-407 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541815(US11267824, Example 34a)
Affinity DataIC50:  19.5nMAssay Description:IDO1: Recombinant full-length human IDO1 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is incubated at a final...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent