BDBM541834 US11267824, Example 52

SMILES Cc1cccc(c1)C(O)c1c(sc2cncn12)C1CC1

InChI Key InChIKey=OXWXOHJHIBLLPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541834   

TargetTryptophan 2,3-dioxygenase(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541834(US11267824, Example 52)
Affinity DataIC50: 22.3nMAssay Description:TDO2: Recombinant human TDO comprising amino acids 19-407 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541834(US11267824, Example 52)
Affinity DataIC50: 64.8nMAssay Description:IDO1: Recombinant full-length human IDO1 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is incubated at a final...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent