BDBM542122 US11274090, Example 24 Isomer 1

SMILES COc1cc(ccc1NC(=O)[C@@H](NCCc1ccc(cc1)C#N)c1ccccc1)-c1cnn(C)c1

InChI Key InChIKey=MXRSOIOJIZKLCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542122   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 542122BDBM542122(US11274090, Example 24 Isomer 1)
Affinity DataIC50: 5.00E+3nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent