BDBM542221 US11274090, Example 64 Isomer 2

SMILES CCN(CC)C(=O)C1CCN(CC1)c1ccc(NC(=O)[C@H](NCCc2ccc(cc2)C#N)c2ccccc2)nc1

InChI Key InChIKey=NNYGPALKDBXNEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542221   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 542221BDBM542221(US11274090, Example 64 Isomer 2)
Affinity DataIC50: 568nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent