BDBM5423 CHEMBL2057594::US8530490, 135

SMILES COc1cccc(c1)S(=O)(=O)NC(C)(C)CCCOCn1ccc(=O)[nH]c1=O

InChI Key InChIKey=PYDAKBNJFHKEOT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5423   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5423(CHEMBL2057594 | US8530490, 135)
Affinity DataIC50: 1.12E+3nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2013
Entry Details
US Patent

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM5423(CHEMBL2057594 | US8530490, 135)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed