BDBM543473 (((6-chloro-5-(2'-hydroxy-[1,1'-biphenyl]-4- yl)-1H-imidazo[4,5-b]pyridin-2- yl)thio)methyl)phosphonic acid::US11279702, Compound 4

SMILES Oc1ccccc1-c1ccc(cc1)-c1nc2nc(SCP(O)(O)=O)[nH]c2cc1Cl

InChI Key InChIKey=YRFIGAZVNQNSGN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543473   

LigandPNGBDBM543473(US11279702, Compound 4 | (((6-chloro-5-(2'-hydroxy...)
Affinity DataEC50:  0.550nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent