BDBM543755 US11279703, TABLE 6.345

SMILES CN1CCN2C(Cc3cc(Nc4ncc5scc(-c6cccc(NS(=O)(=O)C(C)(C)C)c6)c5n4)ccc23)C1

InChI Key InChIKey=WXRVGHDMPFXKBS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 543755   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543755(US11279703, TABLE 6.345)
Affinity DataIC50:  2nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Aptose Biosciences

US Patent
LigandPNGBDBM543755(US11279703, TABLE 6.345)
Affinity DataIC50:  607nMAssay Description:1. Add 20 μl of the diluted compound to each well of the 384-well opti plate2. Tap the plate gently3. Add 10 μl of the enzyme to each well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent