BDBM54393 2,2-dimethyl-N-[N'-(5-methyl-1,3-benzoxazol-2-yl)amidino]propionamide::2,2-dimethyl-N-[N'-(5-methyl-1,3-benzoxazol-2-yl)carbamimidoyl]propanamide::MLS000767476::N-(2,2-Dimethyl-propionyl)-N'-(5-methyl-benzooxazol-2-yl)-guanidine::N-[amino-[(5-methyl-1,3-benzoxazol-2-yl)imino]methyl]-2,2-dimethylpropanamide::SMR000429824::cid_3390551

SMILES Cc1ccc2oc(N=C(N)NC(=O)C(C)(C)C)nc2c1

InChI Key InChIKey=FEGRDSCRSPKTQN-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 54393   

TargetTumor necrosis factor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 54393BDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)
Affinity DataIC50: 39.1nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 54393BDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)
Affinity DataIC50: 94.9nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 54393BDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)
Affinity DataEC50:  310nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetTumor necrosis factor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 54393BDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)
Affinity DataIC50: 313nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 54393BDBM54393(cid_3390551 | N-[amino-[(5-methyl-1,3-benzoxazol-2...)
Affinity DataIC50: 4.71E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay