BDBM546785 US11292791, Example 58::methyl (S)-7-methyl-2-((R)-1-phenylethyl)-3-(piperidin-4-yl)-3,7,8,9-tetrahydro-6H-imidazo[4,5-f]quinoline-6-carboxylate and methyl (S)-7-methyl-2-((S)-1-phenylethyl)-3-(piperidin-4-yl)-3,7,8,9-tetrahydro-6H-imidazo[4,5-f]quinoline-6-carboxylate

SMILES COC(=O)N1[C@@H](C)CCc2c1ccc1n(C3CCNCC3)c(nc21)[C@H](C)c1ccccc1

InChI Key InChIKey=FBKHAHZAYVRQKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 546785   

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 546785BDBM546785(methyl (S)-7-methyl-2-((R)-1-phenylethyl)-3-(piper...)
Affinity DataIC50: 550nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 546785BDBM546785(methyl (S)-7-methyl-2-((R)-1-phenylethyl)-3-(piper...)
Affinity DataIC50: 5.05E+4nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent