BDBM547715 US11292792, CMPD # I-45

SMILES CN(CCCOCC#Cc1ccc2n(C3CCC(=O)NC3=O)c3ncccc3c2c1)C(=O)OC(C)(C)C

InChI Key InChIKey=HZJWFCZECUWBMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547715   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 547715BDBM547715(US11292792, CMPD # I-45)
Affinity DataIC50: 20nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent