BDBM548026 WO2022091056, Example 18::WO2022091056, Example 20

SMILES Cc1c(c(Cl)cc[n+]1[O-])-c1ccc(NC(=O)[C@@H](NC(=O)c2ccnn2C)C2CC[C@@H](CC2)C(F)(F)F)cc1

InChI Key InChIKey=AWVICPDTTOOHEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 548026   

TargetInterleukin-17 receptor A/(Human)
Novartis

WIPO
LigandPNGBDBM548026(WO2022091056, Example 20 | WO2022091056, Example 1...)
Affinity DataIC50: 25nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Novartis

WIPO
LigandPNGBDBM548026(WO2022091056, Example 20 | WO2022091056, Example 1...)
Affinity DataIC50: 680nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056