BDBM549298 1-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]pyrimi- din-5-ium-4- yl)amino]cyclo- butane-carbonitrile::US11299497, Example 13

SMILES CC[C@@H](C)Nc1nc(nc2CC[S@@+]([O-])c12)N(C)CCC1CCOCC1

InChI Key InChIKey=PINSGUVBGLYLQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549298   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [380-741](Human)
Union Therapeutics

US Patent
LigandPNGBDBM549298(1-[(2-chloro-5- oxido-6,7-dihydro- thieno[3,2-d]py...)
Affinity DataIC50: 30nMAssay Description:The human PDE41 Dcatalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent