BDBM5507 6-{[2-(propan-2-yl)-1,3-dioxolan-2-yl]methoxy}-9H-purin-2-amine::O6-Substituted Guanine Deriv. 48

SMILES CC(C)C1(COc2nc(N)nc3nc[nH]c23)OCCO1

InChI Key InChIKey=GMUWLCGLHSIIIC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5507   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5507(6-{[2-(propan-2-yl)-1,3-dioxolan-2-yl]methoxy}-9H-...)
Affinity DataIC50: 3.90E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM5507(6-{[2-(propan-2-yl)-1,3-dioxolan-2-yl]methoxy}-9H-...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5507(6-{[2-(propan-2-yl)-1,3-dioxolan-2-yl]methoxy}-9H-...)
Affinity DataIC50: 6.50E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed