BDBM550809 7-(4-Fluorophenyl)-8-(2-methyl-6-(trifluoromethyl)pyridin-4-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 16::US11312705, Example 16

SMILES Cc1cc(cc(n1)C(F)(F)F)-c1c(nc(N)n2cnnc12)-c1ccc(F)cc1

InChI Key InChIKey=QRTTTWQYKSPJCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550809   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550809(7-(4-Fluorophenyl)-8-(2-methyl-6-(trifluoromethyl)...)
Affinity DataIC50:  0.630nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550809(7-(4-Fluorophenyl)-8-(2-methyl-6-(trifluoromethyl)...)
Affinity DataIC50:  122nMAssay Description:CHO-K1/A2bR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 1 mg/ml G418. The cells were digested with the cell separati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550809(7-(4-Fluorophenyl)-8-(2-methyl-6-(trifluoromethyl)...)
Affinity DataIC50:  0.630nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent