BDBM550817 8-(2-Chloro-6-(trifluoromethyl)pyridin-4-yl)-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 23::US11312705, Example 23

SMILES Nc1nc(-c2ccccc2)c(-c2cc(Cl)nc(c2)C(F)(F)F)c2nncn12

InChI Key InChIKey=WKLXOWXTEYEASY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550817   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550817(8-(2-Chloro-6-(trifluoromethyl)pyridin-4-yl)-7-phe...)
Affinity DataIC50:  0.230nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent