BDBM55083 N-[3-chloranyl-4-[(2-chlorophenyl)carbonylamino]phenyl]pyridine-2-carboxamide::N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]picolinamide::N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]pyridine-2-carboxamide::N-[3-chloro-4-[[(2-chlorophenyl)-oxomethyl]amino]phenyl]-2-pyridinecarboxamide::VU0366037-2::cid_46869941

SMILES Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl

InChI Key InChIKey=MTELUFOIWGSEFF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 55083   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55083(N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]pyrid...)
Affinity DataEC50:  517nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55083(N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]pyrid...)
Affinity DataEC50:  529nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55083(N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]pyrid...)
Affinity DataEC50:  570nMAssay Description:Positive allosteric modulation of rat mGluR4 expressed in CHO cells coexpressing Gqi5 assessed as calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55083(N-[3-chloro-4-[(2-chlorobenzoyl)amino]phenyl]pyrid...)
Affinity DataEC50:  750nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay