BDBM550855 7-(4-Chlorophenyl)-8-(2-(difluoromethyl)-6-methylpyridin-4-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 52::US11312705, Example 52

SMILES Cc1cc(cc(n1)C(F)F)-c1c(nc(N)n2cnnc12)-c1ccc(Cl)cc1

InChI Key InChIKey=ZGEDUFUHGOFADQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 550855   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550855(7-(4-Chlorophenyl)-8-(2-(difluoromethyl)-6-methylp...)
Affinity DataIC50:  0.480nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550855(7-(4-Chlorophenyl)-8-(2-(difluoromethyl)-6-methylp...)
Affinity DataIC50: >104nMAssay Description:CHO-K1/A3R cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 10 μg/ml puromycin. The cells were digested with the cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550855(7-(4-Chlorophenyl)-8-(2-(difluoromethyl)-6-methylp...)
Affinity DataIC50:  41nMAssay Description:CHO-K1/A1R cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 1 mg/ml G418. The cells were digested with the cell separatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550855(7-(4-Chlorophenyl)-8-(2-(difluoromethyl)-6-methylp...)
Affinity DataIC50:  0.480nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent