BDBM55095 N-[3-chloranyl-4-[3-methyl-2,5-bis(oxidanylidene)-3-phenyl-pyrrolidin-1-yl]phenyl]pyridine-2-carboxamide::N-[3-chloro-4-(2,5-diketo-3-methyl-3-phenyl-pyrrolidino)phenyl]picolinamide::N-[3-chloro-4-(3-methyl-2,5-dioxo-3-phenyl-1-pyrrolidinyl)phenyl]-2-pyridinecarboxamide::N-[3-chloro-4-(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)phenyl]pyridine-2-carboxamide::VU0404997-2::cid_46869952

SMILES CC1(CC(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1Cl)c1ccccc1

InChI Key InChIKey=VVBFAZRDUJRAAU-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 55095   

TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55095(cid_46869952 | N-[3-chloranyl-4-[3-methyl-2,5-bis(...)
Affinity DataEC50:  536nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptor by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM55095(cid_46869952 | N-[3-chloranyl-4-[3-methyl-2,5-bis(...)
Affinity DataEC50:  540nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55095(cid_46869952 | N-[3-chloranyl-4-[3-methyl-2,5-bis(...)
Affinity DataEC50:  771nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM55095(cid_46869952 | N-[3-chloranyl-4-[3-methyl-2,5-bis(...)
Affinity DataEC50:  837nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay