BDBM551557 (R or S)-7,9-difluoro-2-(1-(1-methyl-1H-pyrazol-4-yl) piperidin-3-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine::US11312719, Example 103

SMILES Cn1cc(cn1)N1CCCC(C1)c1nc2c3cc(F)cc(F)c3nc(N)n2n1

InChI Key InChIKey=VINJVTSUJSHSLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551557   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551557((R or S)-7,9-difluoro-2-(1-(1-methyl-1H-pyrazol-4-...)
Affinity DataIC50:  137nMAssay Description:The reported affinity of the compounds of the invention for the human A2b adenosine receptor was determined experimentally using a radioligand filtra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551557((R or S)-7,9-difluoro-2-(1-(1-methyl-1H-pyrazol-4-...)
Affinity DataIC50:  0.5nMAssay Description:148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test compound) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent