BDBM551666 (2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino-7,9- difluoro-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-5- methylpiperidin-1-yl)-3-methyl-1H-pyrazol-1-yl)butan-2-ol::US11312719, Example 212::US11312719, Example 213::US11312719, Example 214::US11312719, Example 215

SMILES CC(O)C(C)n1cc(N2CC(C)CC(C2)c2nc3c4cc(F)cc(F)c4nc(N)n3n2)c(C)n1

InChI Key InChIKey=UYBODVMCUMUYOB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 551666   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  122nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  331nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50: >1.00E+4nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  27.5nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  34.1nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  0.400nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551666((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  0.5nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent