BDBM551678 (2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino-9- fluoro-7-methoxy-[1,2,4]triazolo[1,5-c]quinazolin-2-yl)-5- methylpiperidin-1-yl)-3-methyl-1H-pyrazol-1-yl)butan-2-ol::US11312719, Example 224::US11312719, Example 225::US11312719, Example 226::US11312719, Example 227

SMILES COc1cc(F)cc2c3nc(nn3c(N)nc12)C1CC(C)CN(C1)c1cn(nc1C)C(C)C(C)O

InChI Key InChIKey=OELGWNKAAODVMT-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 551678   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  0.400nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  13.1nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  0.400nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  5.07E+3nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  17.6nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  1.61E+3nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  40.2nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM551678((2S,3S or 2R,3R)-3-(4-((3R,5S or 3S,5R)-3-(5-amino...)
Affinity DataIC50:  12.1nMAssay Description:The ability of compounds to antagonize human A2A and A2B adenosine receptors was determined using a kit to measure changes in intracellular cyclic AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent