BDBM551840 US11312722, Compound 130

SMILES Cn1nc(cc1Nc1cc(O)cc(O)c1C(=O)N1Cc2ccccc2C1)-c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=MPIQGZIHDNZLAO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551840   

TargetHeat shock protein 90 homolog(Yeast)
Trustees of Boston University

US Patent
LigandPNGBDBM551840(US11312722, Compound 130)
Affinity DataEC50:  134nMAssay Description:EC50 values were determined by FP-based equilibrium competition assay performed in 384-well format using whole cell lysates prepared from C. neoforma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetHsp90 chaperone protein kinase-targeting subunit(Cryptococcus neoformans var. neoformans serotype D...)
Trustees of Boston University

US Patent
LigandPNGBDBM551840(US11312722, Compound 130)
Affinity DataEC50:  5.40E+3nMAssay Description:EC50 values were determined by FP-based equilibrium competition assay performed in 384-well format using whole cell lysates prepared from C. neoforma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent