BDBM551930 1-(3-amino-2- (1,2,3,4- tetrahydro- quinoline-4- carbonyl)- 6,7-dihydro-2H- pyrazolo[4,3- c]pyridin-5(4H)- yl)ethanone::US11312723, Example 95

SMILES CC(=O)N1CCc2nn(C(=O)C3CCNc4ccccc34)c(N)c2C1

InChI Key InChIKey=RYRKADUXSJGUIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551930   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551930BDBM551930(1-(3-amino-2- (1,2,3,4- tetrahydro- quinoline-4- c...)
Affinity DataIC50: 700nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetProthrombin(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551930BDBM551930(1-(3-amino-2- (1,2,3,4- tetrahydro- quinoline-4- c...)
Affinity DataIC50: 5.00E+4nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent