BDBM551949 US11312723, Example 116::benzyl 3-amino- 2-(1,2,3,4- tetrahydro- quinoline-4- carbonyl)- 4,5-dihydro-2H- pyrazolo[3,4- c]pyridine- 6(7H)- carboxylate

SMILES Nc1c2CCN(Cc2nn1C(=O)C1CCNc2ccccc12)C(=O)OCc1ccccc1

InChI Key InChIKey=HMUOHKZKEGEALV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551949   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551949BDBM551949(benzyl 3-amino- 2-(1,2,3,4- tetrahydro- quinoline-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetProthrombin(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551949BDBM551949(benzyl 3-amino- 2-(1,2,3,4- tetrahydro- quinoline-...)
Affinity DataIC50: 1.70E+4nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent