BDBM551951 (3-amino- 4,5,6,7- tetrahydro- pyrazolo[3,4- c]pyridin-2- yl)(1,2,3,4- tetrahydro- quinolin-4- yl)methanone::US11312723, Example 118

SMILES Nc1c2CCNCc2nn1C(=O)C1CCNc2ccccc12

InChI Key InChIKey=KZSJXASCYFBPAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551951   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551951BDBM551951((3-amino- 4,5,6,7- tetrahydro- pyrazolo[3,4- c]pyr...)
Affinity DataIC50: 600nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetProthrombin(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551951BDBM551951((3-amino- 4,5,6,7- tetrahydro- pyrazolo[3,4- c]pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent