BDBM551973 (3-amino-6-(2,2- difluoroethyl- sulfonyl)- 4,5,6,7- tetrahydro- pyrazolo[3,4- c]pyridin-1- yl)(6-fluoro- 1,2,3,4- tetrahydro- quinolin-4- yl)methanone::US11312723, Example 143

SMILES Nc1nn(C(=O)C2CCNc3ccc(F)cc23)c2CN(CCc12)S(=O)(=O)CC(F)F

InChI Key InChIKey=VOEQSNUSTSELBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551973   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551973BDBM551973((3-amino-6-(2,2- difluoroethyl- sulfonyl)- 4,5,6,7...)
Affinity DataIC50: 1.70E+4nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent