BDBM552061 US11312726, Compound 32

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)Nc1ccc3C(=O)OCc3c1)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=OLAQRMVYAWHVED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 552061   

TargetBromodomain-containing protein 4 [349-460](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552061(US11312726, Compound 32 | US12344620, Compound of ...)
Affinity DataIC50: 10nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [342-460](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552061(US11312726, Compound 32 | US12344620, Compound of ...)
Affinity DataIC50: 10nMAssay Description:1) using BRD4-BD1 protein and BRD4-BD2 protein from BPS company for the experiments; as well as polypeptides from ANASPEC company; detection reagents...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552061(US11312726, Compound 32 | US12344620, Compound of ...)
Affinity DataIC50: 66nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [49-170](Human)
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM552061(US11312726, Compound 32 | US12344620, Compound of ...)
Affinity DataIC50: 66nMAssay Description:1) using BRD4-BD1 protein and BRD4-BD2 protein from BPS company for the experiments; as well as polypeptides from ANASPEC company; detection reagents...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent