BDBM5525 2-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}ethan-1-ol::6-Cyclohexylmethoxy-2-(2-hydroxyethylamino)purine::O6-Cyclohexylmethylguanine deriv. 10

SMILES OCCNc1nc(OCC2CCCCC2)c2[nH]cnc2n1

InChI Key InChIKey=IKXYTZZLTZPRJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5525   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5525(2-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}etha...)
Affinity DataIC50: 2.80E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5525(2-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}etha...)
Affinity DataIC50: 3.20E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed