BDBM552523 WO2022098809, Example 4-10

SMILES COc1cc2CCN(C)Cc2cc1Nc1ncc(C(N)=O)c(Nc2ccc(F)cc2F)n1

InChI Key InChIKey=VVDOJOBMRWWNIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552523   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM552523(WO2022098809, Example 4-10)
Affinity DataIC50:  1.34nMAssay Description: Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to colum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed