BDBM552550 WO2022098809, Example 5-2

SMILES COc1cc2CCN(CC(C)(C)O)Cc2cc1Nc1ncc(C(N)=O)c(Nc2c(C)cccc2F)n1

InChI Key InChIKey=GTEMXMUCFALYFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552550   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Merck Sharp &Amp

WIPO
LigandPNGBDBM552550(WO2022098809, Example 5-2)
Affinity DataIC50:  2.54nMAssay Description: Compounds are serially diluted (3-fold in 100% DMSO) across a 384-well polypropylene source plated from column 3 to column 12 and column 13 to colum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed