BDBM552591 N-[3-({4-[3-(3-chloro-2-methoxyanilino)-4-oxo-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]pyridin-3-yl}oxy)propyl]prop-2-enamide::WO2022101184, Example 4

SMILES COc1c(Cl)cccc1Nc1c([nH]c2CCNC(=O)c12)-c1ccncc1OCCCNC(=O)C=C

InChI Key InChIKey=LJSAJZBTNRLHOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552591   

TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
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WIPO
LigandPNGBDBM552591(WO2022101184, Example 4 | N-[3-({4-[3-(3-chloro-2-...)
Affinity DataIC50: 0.310nMAssay Description: Inhibitory activity of compounds of the present invention against an Epidermal Growth Factor Receptor (EGFR) with an insertion of the amino acids se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101184