BDBM552606 WO2022101377, Example 5

SMILES C[C@@H]1CN(C[C@@H](C)O1)C(=O)[C@@H]1Cc2sc-3c([C@@H](NCc4nnc(C)n-34)c3ccccc3Cl)c2C1

InChI Key InChIKey=YRHFRCNVCJJLCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552606   

TargetPlatelet-activating factor receptor(Human)
Boehringer Ingelheim International

WIPO
LigandPNGBDBM552606(WO2022101377, Example 5)
Affinity DataIC50: 8.20nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377