BDBM552617 WO2022101377, Example 16

SMILES Cc1nnc2CN[C@H](c3c4C[C@@H](Cc4sc3-n12)C(=O)N[C@@H]1CCC(F)(F)C1)c1ccccc1Cl

InChI Key InChIKey=ZJOQVCVKXZPHIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552617   

TargetPlatelet-activating factor receptor(Human)
Boehringer Ingelheim International

WIPO
LigandPNGBDBM552617(WO2022101377, Example 16)
Affinity DataIC50: 1.40nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377