BDBM552651 WO2022101377, Example 50
SMILES CCC12CC(C1)(C2)NC(=O)[C@@H]1Cc2sc-3c([C@@H](NCc4nnc(C)n-34)c3ccccc3Cl)c2C1
InChI Key InChIKey=MXVBMXMJYXTVHU-IBYLJOCYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 552651
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Boehringer Ingelheim International
WIPO
Boehringer Ingelheim International
WIPO
Affinity DataIC50: 0.5nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair