BDBM552667 WO2022101377, Example 66

SMILES Cc1nnc2CNC(c3c4C[C@@H](Cc4sc3-n12)C(=O)N1CCCC2(CC2)C1)c1ccccc1Cl

InChI Key InChIKey=KICIXKHGULOEKB-GZWBLTSWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552667   

TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Boehringer Ingelheim International

WIPO
LigandPNGBDBM552667(WO2022101377, Example 66)
Affinity DataIC50:  2.70nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed