BDBM552667 WO2022101377, Example 66
SMILES Cc1nnc2CNC(c3c4C[C@@H](Cc4sc3-n12)C(=O)N1CCCC2(CC2)C1)c1ccccc1Cl
InChI Key InChIKey=KICIXKHGULOEKB-GZWBLTSWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 552667
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Boehringer Ingelheim International
WIPO
Boehringer Ingelheim International
WIPO
Affinity DataIC50: 2.70nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair