BDBM552689 (2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-oxopropan-2-yl)-l-((S)-2-cyclobutyl-2-(4-cyclopropyl-lH-l,2,3-triazol-l-yl)acetyl)-4-hydroxypyrrolidine-2-carboxamide ( Compound 4)::WO2022103411, Example S4

SMILES NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)C1C[C@@H](O)CN1C(=O)[C@H](C1CCC1)n1cc(nn1)C1CC1

InChI Key InChIKey=DXCFMJMLSKBAGH-VFLSMOPBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552689   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

WIPO
LigandPNGBDBM552689((2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-...)
Affinity DataIC50:  190nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed