BDBM552701 WO2022103411, Example S17::l-((S)-l-((2S,4R)-2-(((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-oxopropan-2-yl)carbamoyl)-4-hydroxypyrrolidin-l-yl)-3,3-dimethyl-l-oxobutan-2-yl)-N-methyl-lH-l,2,3-triazole-4-carboxamide (Compound 17)

SMILES CNC(=O)c1cn(nn1)[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@H](Cc1ccc(cc1)-c1ccccc1)C(N)=O)C(C)(C)C

InChI Key InChIKey=JIFYGNWBOUYLMM-YQIMAOPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552701   

Targetvon Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Genentech

WIPO
LigandPNGBDBM552701(WO2022103411, Example S17 | l-((S)-l-((2S,4R)-2-((...)
Affinity DataIC50:  2.21E+3nMAssay Description:The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed