BDBM552790 (R)-3-(3-(2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)thiazol-4-yl)phenyl)-2,3-dihydrofuro[3,2-b]pyridin-3-ol.::WO2022104348, Example 17
SMILES O[C@@]1(OCc2cccnc12)c1cccc(c1)-c1csc(n1)-c1c[nH]c2nccnc12
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 552790
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica
WIPO
Janssen Pharmaceutica
WIPO
Affinity DataIC50: <100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in...More data for this Ligand-Target Pair