BDBM552811 (R)-8-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol-4-yl)phenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-8-ol.::WO2022104348, Example 38

SMILES O[C@]1(CCCn2ccnc12)c1cccc(c1)-c1csc(n1)-c1c[nH]c2ncccc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552811   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Janssen Pharmaceutica

WIPO
LigandPNGBDBM552811((R)-8-(3-(2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)thiazol...)
Affinity DataIC50: <100nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreenŽ (ascreen) format (Perkin Elmer). All compound6 tested were dissolved in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed