BDBM553047 4-fluoro-N-[4-fluoro-5- (2-morpholin-4- ylpyrimidin-5-yl)-2-[rac- (3R)-3,4- dimethylpiperazin-1- yl]phenyl]-3,5- dimethylbenzamide::US11319299, Example 97

SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1cc(C)c(F)c(C)c1)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=QTPUIDDNZCGPCD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553047   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553047BDBM553047(4-fluoro-N-[4-fluoro-5- (2-morpholin-4- ylpyrimidi...)
Affinity DataKd:  2.21nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent