BDBM553096 N-[4-fluoro-2-[rac- (3R,5S)-3,4,5- trimethylpiperazin-1-yl]- 5-[4-(trifluoromethoxy) phenyl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 145

SMILES C[C@@H]1CN(c2cc(F)c(-c3ccc(OC(F)(F)F)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C

InChI Key InChIKey=YWOJOPOTDSDSBS-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553096   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553096BDBM553096(N-[4-fluoro-2-[rac- (3R,5S)-3,4,5- trimethylpipera...)
Affinity DataKd:  6.83nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent