BDBM553221 US11319299, Example 276::ethyl 2-[4-[2-fluoro-5- [[6-oxo-4-(trifluoromethyl)- 1H-pyridine-3-carbonyl] amino]-4-[rac-(3R,5S)- 3,4,5-trimethylpiperazin-1- yl]phenyl]-3,6-dihydro-2H- pyridin-1-yl]pyrimidine-4- carboxylate

SMILES CCOC(=O)c1ccnc(N2CC=C(c3cc(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c(N4C[C@@H](C)N(C)[C@@H](C)C4)cc3F)CC2)n1

InChI Key InChIKey=KOMYZHWERXGMSB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553221   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553221BDBM553221(ethyl 2-[4-[2-fluoro-5- [[6-oxo-4-(trifluoromethyl...)
Affinity DataKd:  1.67nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent