BDBM553244 N-[4-fluoro-5-[6-(4- methylpiperazin-1- yl)pyridin-3-yl]-2-[rac-(3R)- 3,4-dimethylpiperazin-1- yl]phenyl]-1-methyl-6-oxo- (trifluoromethyl)pyridine- 3-carboxamide::US11319299, Example 301

SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1cn(C)c(=O)cc1C(F)(F)F)-c1ccc(nc1)N1CCN(C)CC1

InChI Key InChIKey=VWDUQBBEOGKQCJ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553244   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553244BDBM553244(N-[4-fluoro-5-[6-(4- methylpiperazin-1- yl)pyridin...)
Affinity DataKd:  5.26nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent