BDBM553248 4-[4-[5-[2-fluoro-5-[[6- oxo-4-(trifluoromethyl)- 1H-pyridine-3-carbonyl]amino]- 4-[rac-(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]pyrimidin-2- yl]piperazin-1-yl]-4- oxobutanoic acid::US11319299, Example 306

SMILES C[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCN(C(=O)CCC(=O)O)CC4)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C

InChI Key InChIKey=BCDPUDFJPKUALQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553248   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553248BDBM553248(4-[4-[5-[2-fluoro-5-[[6- oxo-4-(trifluoromethyl)- ...)
Affinity DataKd:  0.789nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent