BDBM553251 1-ethyl-N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2-[rac-(3R,5S)- 3,4,5-trimethylpiperazin- 1-yl]phenyl]-6-oxo-4- (trifluoromethyl)pyridine- 3-carboxamide::US11319299, Example 315

SMILES CCn1cc(C(=O)Nc2cc(c(F)cc2N2C[C@H](C)N(C)[C@H](C)C2)-c2cnc(nc2)N2CCOCC2)c(cc1=O)C(F)(F)F

InChI Key InChIKey=HJYQEVDQXZSVMQ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553251   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553251BDBM553251(1-ethyl-N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin-...)
Affinity DataKd:  8.49nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent