BDBM553271 N-[4-fluoro-2-[rac-(3R)- 3,4-dimethylpiperazin-1- yl]-5-[2-[rac-(3R)-3- methylmorpholin-4- yl]pyrimidin-5-yl]phenyl]- 6-oxo-4-(trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 337

SMILES C[C@H]1CN(c2cc(F)c(-c3cnc(N4CCOC[C@@H]4C)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CCN1C

InChI Key InChIKey=HEVWPLPEWXVHTO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553271   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553271BDBM553271(N-[4-fluoro-2-[rac-(3R)- 3,4-dimethylpiperazin-1- ...)
Affinity DataKd:  1.16nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent