BDBM553279 N-[4-fluoro-2-[rac-(3R)- 3,4-dimethylpiperazin-1- yl]-5-[2-[rac-(2R)-2- propan-2-ylmorpholin-4- yl]pyrimidin-5-yl]phenyl]-6- oxo-4-(trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 347

SMILES CC(C)[C@H]1CN(c2ncc(-c3cc(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c(N4CCN(C)[C@@H](C)C4)cc3F)cn2)CCO1

InChI Key InChIKey=FSBIOOHONRSUDG-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553279   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553279BDBM553279(N-[4-fluoro-2-[rac-(3R)- 3,4-dimethylpiperazin-1- ...)
Affinity DataKd:  0.606nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent