BDBM553306 N-[5-[2-(dimethylamino) pyrimidin-5-yl]-4-fluoro-2-[rac- (3R,5S)-3,4,5-trimethylpiperazin- 1-yl]phenyl]-4-fluoro-2- (trifluoromethyl)benzamide::US11319299, Example 380

SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1ccc(F)cc1C(F)(F)F)-c1cnc(nc1)N(C)C

InChI Key InChIKey=MAKIKSDYKJDQRG-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553306   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553306BDBM553306(N-[5-[2-(dimethylamino) pyrimidin-5-yl]-4-fluoro-2...)
Affinity DataKd:  1.70nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent