BDBM553344 N-[4-fluoro-5-[2-[rac- (2R,6S)-2,6-dimethylmorpholin- 4-yl]pyrimidin-5-yl]-2-[rac- (3S)-3-[ethyl(methyl)amino] pyrrolidin-1-yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H-pyridine-3- carboxamide::US11319299, Example 418

SMILES CCN(C)[C@@H]1CCN(c2cc(F)c(-c3cnc(N4C[C@@H](C)O[C@@H](C)C4)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C1

InChI Key InChIKey=RCFWLWDIJBXJBT-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553344   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553344BDBM553344(N-[4-fluoro-5-[2-[rac- (2R,6S)-2,6-dimethylmorphol...)
Affinity DataKd:  1.05nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent