BDBM553352 N-[4-fluoro-2-[rac-(3S)-3- (dimethylamino)pyrrolidin-1- yl]-5-[2-[rac-(2R,6S)- 2,6-dimethylmorpholin-4- yl]pyrimidin-5-yl]phenyl]-1- methyl-6-oxo-4-(trifluoromethyl) pyridine-3-carboxamide::US11319299, Example 426

SMILES C[C@H]1CN(C[C@@H](C)O1)c1ncc(cn1)-c1cc(NC(=O)c2cn(C)c(=O)cc2C(F)(F)F)c(cc1F)N1CC[C@H](C1)N(C)C

InChI Key InChIKey=IYBGGAZGPWXFKR-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553352   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553352BDBM553352(N-[4-fluoro-2-[rac-(3S)-3- (dimethylamino)pyrrolid...)
Affinity DataKd:  10.9nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent